The WVU Shared Research Facilities Microfabrication Cleanroom is contributing to a five-year, $2.20 million NIH/National Cancer Institute R01 led by Principal Investigator Dr. Margaret Bennewitz, with Dr. Trieu Nguyen serving as Co-Principal Investigator and leading the microfabrication component.
Dr. Nguyen, Co-PI and Manager of the SRF Microfabrication Cleanroom, will direct the in-house design and fabrication of custom 3D “tumor-on-a-chip” devices. These miniature devices will grow small clusters of breast cancer cells beside blood-vessel-like channels carrying flowing nutrients, creating controlled laboratory models of how an imaging agent moves from the bloodstream into a tumor.