Mass spectrometry is a modern analytical tool that studies molecules based on their mass-to-charge ratio. It provides detailed information about the composition, structure, and properties of a wide range of substances, from small molecules to large biomolecules. Mass spectrometry can determine the elemental composition of a compound, identify unknown compounds by comparing their mass spectra to reference databases, measure isotopic patterns to confirm the authenticity of substances, and quantify the number of specific compounds in a sample. It can also be coupled with other separation techniques to enhance its capabilities, making it an indispensable tool in various scientific fields, including chemistry, biology, pharmacology, and environmental science.
The following table lists available mass spectrometers on the WVU campus:
| Description | Contact and location |
|
Thermo Q Exactive Orbitrap Mass Spectrometer Capable of both targeted and untargeted analysis with up to 140,000 resolving power and 5 ppm mass tolerance. Mass range is between 50 to 6000 m/z. It can analyze small molecules and large proteins, It employs a heated electrospray ionization (ESI) source that makes it ideal for direct infusion and LC-MS/MS applications. |
Dr. Bo Xue CRL 381, Chemistry Research Lab |
|
Thermo LTQ Linear Ion Trap Mass Spectrometer A robust system suitable for initial analysis and screening of large quantity of samples at a lower cost. The mass ranges from 50 to 4,000 m/z and upto 10000 resolving power. This system utilizes a heated Electrospray ionization (ESI) source, suitable for LC-MS applications. |
Dr. Bo Xue CRL 381, Chemistry Research Lab |
|
Agilent 6538 UHD Q-TOF Mass Spectrometer with up to 20-10000 Da mass range and up to 40000 resolving power, suitable for large molecule analysis and fast LC-MS analysis. (Currently does not connect to a UHPLC) |
Prof. Glen Jackson
1600 University Ave, Morgantown, WV 26506 |
|
Thermo Scientific LTQ Velos Pro Dual-Pressure Linear Ion Trap Mass Spectrometer A robust machine with improved resolving power compared to a base LTQ model. It provides 50-4000 mass range and up to 20000 resolving power. Suitable for an extensive range of basic analytical applications. |
Prof. Glen Jackson
1600 University Ave, Morgantown, WV 26506 |
|
Agilent 5977B GC/MSD Versatile GC-MS system suitable for volatile analytes. Mass range is from 0.6 to 1091 and the FWHM is 0.4 Da. Scan rate is up to 20000 Da/s. |
Prof. Glen Jackson
1600 University Ave, Morgantown, WV 26506 |
|
SCIEX Triple Quad 5500 LC-MS/MS A robust quadrupole mass spectrometer ideal for targeted and small molecule analysis. Mass range is 1 to 2000 with FWHM at 0.4 Da. |
Dr. Terrence McManus 500 Medical Center Dr, Morgantown, WV 26505 |
|
JEOL JMS S3000 Spiral This is a MALDI-TOF MS Suitable for quick analysis and large molecules due to superior scan rate (), extended mass range (4-30000 Da) and up to 60,000 resolving power. |
Prof. Mark McLaughlin 500 Medical Center Dr, Morgantown, WV 26505 |
|
Thermo Scientific LCQ Linear Ion Trap Mass Spectrometer 3D ion trap mass spectrometer that is ideal for sample screening. Mass range is from 50 to 2000 with a 0.7 Da FWHM. |
Dr. Anthony DeBastiani 400 Clark Hall, 100 Prospect Street, Morgantown, WV 26506 |
|
Thermo Scientific ISQ EC Single Quadrupole Mass Spectrometer A robust single quadrupole mass spec ideal for volatile analytes. Mass range is from 10 to 1250 with a 0.7 Da FWHM. |
Dr. Anthony DeBastiani 400 Clark Hall, 100 Prospect Street, Morgantown, WV 26506 |
|
Perkin Elmer NexION 2000 This versatile ICP-MS is the go-to instrument for for
metal ion identification. The LLOD is down to 0.25 ng/L with less than 1 cps
background noise. |
Gabriela Perhinschi
|
|
ThermoScientific TSQ Quantis This equipment is reserved for clinical work and not available for any other type of analysis. Mass range is 1-2000 with a FWHM at 0.15 Da. |
Dr. Danyel Tacker |
|
ThermoScientific LTQ XL Linear Trap Mass Spectrometer A robust system with resolving power up to 10000 and mass range from 50-4000. Suitable for first-step analysis and low-cost screening of a large number of samples. |
Prof. Stephen Valentine |
|
Agilent 5977B GC/MSD Versatile GC-MS system suitable for volatile analytes. Mass range is from 0.6 to 1091 and the FWHM is 0.4 Da. Scan rate is up to 20000 Da/s. Suitable for volatile analytes. |
Prof. Joseph Lynch |
|
Thermo Scientific ISQ EC Single Quadrupole Mass Spectrometer A robust single quadrupole mass spec ideal for volatile analytes. Mass range is from 10 to 1250 with a 0.7 Da FWHM. |
Prof. Joseph Lynch |